Variant DetailsVariant: esv3583058 | Internal ID | 18711256 | | Landmark | | | Location Information | | | Cytoband | 18q21.1 | | Allele length | | Assembly | Allele length | | hg38 | 5854 | | hg19 | 5854 |
| | Variant Type | CNV loss | | Copy Number | | | Allele State | | | Allele Origin | | | Probe Count | | | Validation Flag | | | Merged Status | M | | Merged Variants | dgv987e212 | | Supporting Variants | essv9815759, essv9815766, essv9815786, essv9815770, essv9815735, essv9815785, essv9815787, essv9815728, essv9815764, essv9815731, essv9815772, essv9815750, essv9815783, essv9815771, essv9815730, essv9815780, essv9815749, essv9815757, essv9815748, essv9815775, essv9815768, essv9815763, essv9815774, essv9815739, essv9815743, essv9815741, essv9815751, essv9815737, essv9815747, essv9815760, essv9815736, essv9815788, essv9815753, essv9815742, essv9815784, essv9815745, essv9815754, essv9815769, essv9815779, essv9815738, essv9815777, essv9815781, essv9815765, essv9815758, essv9815752, essv9815729, essv9815790, essv9815761, essv9815762, essv9815732, essv9815746, essv9815740, essv9815782, essv9815773, essv9815734, essv9815776 | | Samples | 401799DP, 401474CE, 401005BL, 400268SY, 400132HN, 400094RS, 401077VC, 401487FW, 400906BR, 401911FL, 400506GN, 400595CP, 401931JL, 400629BM, 400325BE, 400425SL, 401253MC, 400360SM, 400588BE, 401239PR, 401908YM, 401214BJ, 400121PL, 401831TW, 400333CC, 401997HB, 400411TG, 400974PS, 400738WM, 402052ZA, 400768MN, 401494PD, 400082SD, 401478RD, 401444LD, 402022SM, 401892MJ, 401587RC, 400258BC, 400520FM, 400135DR, 400788PV, 401677MM, 401057SS, 400837HN, 401287CF, 400267GD, 401438HT, 400328LM, 401240ML, 400271SR, 401153HS, 400540BM, 401480PG, 400152MR, 400234CA | | Known Genes | MAPK4 | | Method | SNP array | | Analysis | We used four separate algorithms to detect CNVs; Affymetrix Chromosome Analysis Suite (ChAS), iPattern, Nexus and Partek. Our primary analysis was performed based on ChAS CNV calls, which were then supported using the remaining three algorithms to construct a confidence set of CNVs. For all algorithms, we have used 8 probes and >1kb as a base line cutoff for CNV detection. | | Platform | Affymetrix CytoScan HD 2.7M array | | Comments | | | Reference | Uddin_et_al_2014 | | Pubmed ID | 25503493 | | Accession Number(s) | esv3583058
| | Frequency | | Sample Size | 873 | | Observed Gain | 0 | | Observed Loss | 56 | | Observed Complex | 0 | | Frequency | n/a |
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